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Oestrogens (eg. oral contraceptives – 1 pill per day) suppress ovarian androgen production and reduce free androgens (Yasmin). |
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Diane 35 or Dianette (1 pill per day). This contains oestrogen (female hormone – similar to contraceptive pills) and a low dose of Cyproterone-acetate (anti-androgen). |
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Cyproteron-acetate (anti-androgen) - 50 -200mg per day. Anti-androgens counteract male hormones. Cyproterone must be used along with an oral contraceptive pill to avoid this happening. Cyproterone is also available in doses that are larger and more effective than the dose found in Diane 35 and Dianette. It is necessary to prevent pregnancy during and for up to 6 months following treatment with anti-androgens as they have potential to damage a developing baby (can cause a male fetus to appear female). |
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Spironolactone (200 mg per day) is a diuretic and it has some anti-androgen activity. It should be taken along with an oral contraceptive pill to avoid pregnancy. Can cause useful improvements in hirsutism in selected cases. |
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Metformin. This drug is normally used in the treatment of diabetes. It has been shown to be beneficial in women with PCOS. |
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Vaniqa cream (eflornithine) applied twice daily slows the growth of facial hair by inhibiting a key enzyme involved in hair growth. |